Which of the following best explains what happens during metaphase? A. The sister chromatids are pulled apart. B. The chromosomes line up. C. The chromosomes coil up and condense. D. The cell is developing and going about its daily activities. Which of the following best explains what happens during metaphase? A. The sister chromatids are pulled apart. B. The chromosomes line up. C. The chromosomes coil up and condense. D. The cell is developing and going about its daily activities.